Issue 22, 2008
From the journal:

Organic & Biomolecular Chemistry

Unusual reactivity of N-acyl imides: N-aroyl-1,2,4-dithiazolidine-3,5-diones as acyl isocyanate equivalents†

Mark E. Wood,*a   Victoria M. Annisa  and  Clifford D. Jonesb  

* Corresponding authors

a School of Biosciences, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter, UK
E-mail: m.e.wood@exeter.ac.uk
Tel: +44 1392 263450

b AstraZeneca, Cancer and Infection Chemistry, Mereside, Alderley Park, Macclesfield, UK

Abstract

Crystalline samples of three N-aroyl-1,2,4-dithiazolidine-3,5-diones have been prepared as the first examples of a novel class of compound that displays the reactivity of an acyl isocyanate when treated with nucleophiles.

Graphical abstract: Unusual reactivity of N-acyl imides: N-aroyl-1,2,4-dithiazolidine-3,5-diones as acyl isocyanate equivalents

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B814677B
Article type
Communication
Submitted
22 Aug 2008
Accepted
18 Sep 2008
First published
01 Oct 2008

Org. Biomol. Chem., 2008,6, 4099-4101

Permissions

Request permissions

Unusual reactivity of N-acyl imides: N-aroyl-1,2,4-dithiazolidine-3,5-diones as acyl isocyanate equivalents

M. E. Wood, V. M. Annis and C. D. Jones, Org. Biomol. Chem., 2008, 6, 4099 DOI: 10.1039/B814677B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements