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Issue 10, 2008
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Formation of artificial lipid bilayers using droplet dielectrophoresis

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Abstract

We describe the formation of artificial bilayer lipid membranes (BLMs) by the controlled, electrical manipulation of aqueous droplets immersed in a lipidalkane solution. Droplet movement was generated using dielectrophoresis on planar microelectrodes covered in a thin insulator. Droplets, surrounded by lipid monolayers, were brought into contact and spontaneously formed a BLM. The method produced BLMs suitable for single-channel recording of membrane protein activity and the technique can be extended to create programmable BLM arrays and networks.

Graphical abstract: Formation of artificial lipid bilayers using droplet dielectrophoresis

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Article information


Submitted
30 Apr 2008
Accepted
05 Aug 2008
First published
13 Aug 2008

Lab Chip, 2008,8, 1617-1620
Article type
Communication

Formation of artificial lipid bilayers using droplet dielectrophoresis

S. Aghdaei, M. E. Sandison, M. Zagnoni, N. G. Green and H. Morgan, Lab Chip, 2008, 8, 1617
DOI: 10.1039/B807374K

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