Issue 7, 2008

Phase equilibria in ternary mixtures of the ionic liquid bmim[BF4], (S)-naproxen and CO2 to determine optimum regions for green processing

Abstract

In order to optimize reaction and separation processes, knowledge of the phase behaviour of the system is of fundamental importance. In this contribution we present the solid–liquid and liquid–vapour equilibria of the ternary system 1-butyl-3-methylimidazolium tetrafluoroborate + (S)-naproxen + carbon dioxide. Five different samples were studied, with CO2 concentrations ranging from 10 to 50 mol%, and pressure and temperature conditions of 1 to 14 MPa, and 310 to 370 K, respectively. It is shown that the amount of CO2 influences not only the location of the homogeneous liquid phase region, but also the extension of the region in which it occurs. Based on the collected experimental data, optimum pressure and temperature conditions can be selected for the precipitation of (S)-naproxen from the ionic liquid in order to improve the efficiency of the separation.

Graphical abstract: Phase equilibria in ternary mixtures of the ionic liquid bmim[BF4], (S)-naproxen and CO2 to determine optimum regions for green processing

Article information

Article type
Paper
Submitted
21 Jan 2008
Accepted
09 Apr 2008
First published
13 May 2008

Green Chem., 2008,10, 762-766

Phase equilibria in ternary mixtures of the ionic liquid bmim[BF4], (S)-naproxen and CO2 to determine optimum regions for green processing

E. Kühne, S. Santarossa, G. Witkamp and C. J. Peters, Green Chem., 2008, 10, 762 DOI: 10.1039/B801068D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements