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Issue 47, 2008
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Caesium fluoride-promoted Stille coupling reaction: an efficient synthesis of 9Z-retinoic acid and its analogues using a practical building block

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Abstract

A highly efficient and rapid total synthesis of 9Z-retinoic acid was accomplished by caesium fluoride-promoted Stille coupling reaction; using a common building block, 9Z-retinoic acid analogues were also prepared by the same method without isomerisation of the Z-double bond.

Graphical abstract: Caesium fluoride-promoted Stille coupling reaction: an efficient synthesis of 9Z-retinoic acid and its analogues using a practical building block

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Publication details

The article was received on 07 Aug 2008, accepted on 23 Sep 2008 and first published on 23 Oct 2008


Article type: Communication
DOI: 10.1039/B813760A
Citation: Chem. Commun., 2008,0, 6330-6332

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    Caesium fluoride-promoted Stille coupling reaction: an efficient synthesis of 9Z-retinoic acid and its analogues using a practical building block

    T. Okitsu, K. Iwatsuka and A. Wada, Chem. Commun., 2008, 0, 6330
    DOI: 10.1039/B813760A

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