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Issue 44, 2008
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Modular synthesis of multivalent glycoarchitectures and their unique selectin binding behavior

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Abstract

Hyperbranched polyglycerols (HPGs) are ideal scaffolds for the multivalent presentation of saccharides, due to their biocompatible, carbohydrate-like properties; here, we report the conjugation of galactose sugar moieties to HPG, and the multivalent effect of these constructs on selectin binding.

Graphical abstract: Modular synthesis of multivalent glycoarchitectures and their unique selectin binding behavior

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Supplementary files

Article information


Submitted
01 Aug 2008
Accepted
11 Sep 2008
First published
03 Oct 2008

Chem. Commun., 2008, 5851-5853
Article type
Communication

Modular synthesis of multivalent glycoarchitectures and their unique selectin binding behavior

I. Papp, J. Dernedde, S. Enders and R. Haag, Chem. Commun., 2008, 5851
DOI: 10.1039/B813414F

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