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Issue 35, 2008
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Dynamic resolution of N-Boc-2-lithiopiperidine

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Dynamic thermodynamic resolution of N-Boc-2-lithiopiperidine is possible using a chiral ligand; the two enantiomers of this organolithium can be resolved with selectivities of up to 85 : 15 from a selection of 26 chiral diamino-alkoxide ligands screened.

Graphical abstract: Dynamic resolution of N-Boc-2-lithiopiperidine

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The article was received on 27 Jun 2008, accepted on 29 Jul 2008 and first published on 08 Aug 2008

Article type: Communication
DOI: 10.1039/B810988E
Citation: Chem. Commun., 2008,0, 4174-4176
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    Dynamic resolution of N-Boc-2-lithiopiperidine

    I. Coldham, S. Raimbault, P. T. Chovatia, J. J. Patel, D. Leonori, N. S. Sheikh and D. T. E. Whittaker, Chem. Commun., 2008, 0, 4174
    DOI: 10.1039/B810988E

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