Jump to main content
Jump to site search

Issue 40, 2008
Previous Article Next Article

Rhodium-catalysed hydroacylation or reductive aldol reactions: a ligand dependent switch of reactivity

Author affiliations

Abstract

The pathway for the combination of enones and β-S-substituted aldehydes using Rh-catalysis can be switched between a hydroacylation reaction or a reductive aldol reaction by simple choice of the phosphine ligand; this catalyst controlled switch allows access to new ketone hydroacylation products; useful 1,4-diketone intermediates for the synthesis of N-, S- and O-heterocycles.

Graphical abstract: Rhodium-catalysed hydroacylation or reductive aldol reactions: a ligand dependent switch of reactivity

Back to tab navigation

Supplementary files

Publication details

The article was received on 27 Jun 2008, accepted on 31 Jul 2008 and first published on 02 Sep 2008


Article type: Communication
DOI: 10.1039/B810935D
Citation: Chem. Commun., 2008,0, 5025-5027

  •   Request permissions

    Rhodium-catalysed hydroacylation or reductive aldol reactions: a ligand dependent switch of reactivity

    J. D. Osborne and M. C. Willis, Chem. Commun., 2008, 0, 5025
    DOI: 10.1039/B810935D

Search articles by author

Spotlight

Advertisements