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Issue 40, 2008
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One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

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Abstract

A novel multicatalytic one-pot process providing trans-cyclopropyl compounds from corresponding aldehydes has been developed and applied to the synthesis of GPR40 small molecule agonists.

Graphical abstract: One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

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Publication details

The article was received on 25 Jun 2008, accepted on 04 Aug 2008 and first published on 12 Sep 2008


Article type: Communication
DOI: 10.1039/B810708D
Chem. Commun., 2008, 4974-4976

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    One-pot approach for the synthesis of trans-cyclopropyl compounds from aldehydes. Application to the synthesis of GPR40 receptor agonists

    M. Davi and H. Lebel, Chem. Commun., 2008, 4974
    DOI: 10.1039/B810708D

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