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Issue 34, 2008
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Target-driven selection in a dynamic nitrone library

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Abstract

Nitrones undergo dynamic exchange in chloroform at room temperature through two mechanisms—hydrolysis and recombination or hydroxylamine addition/elimination; this dynamic exchange is harnessed to select a nitrone-based bis(amidopyridine) receptor for diacids from a group of four nitrones through its binding to a glutaric acid-based target.

Graphical abstract: Target-driven selection in a dynamic nitrone library

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Publication details

The article was received on 08 Apr 2008, accepted on 16 May 2008 and first published on 03 Jul 2008


Article type: Communication
DOI: 10.1039/B805945D
Citation: Chem. Commun., 2008,0, 4076-4078
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    Target-driven selection in a dynamic nitrone library

    S. M. Turega, C. Lorenz, J. W. Sadownik and D. Philp, Chem. Commun., 2008, 0, 4076
    DOI: 10.1039/B805945D

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