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Issue 30, 2008
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SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles†

Andreas M. Nyström,a   Zhiqiang Xu,b   Jinqi Xu,a   Sara Taylor,b   Thalia Nittis,c   Sheila A. Stewart,c   Jeffrey Leonardb  and  Karen L. Wooley*a  
Author affiliations

* Corresponding authors

a Center for Materials Innovation, Department of Chemistry and Department of Radiology, Washington University in Saint Louis, Saint Louis, USA
E-mail: klwooley@artsci.wustl.edu
Fax: +1 314 935-9844
Tel: +1 314 935-7136

b Department of Neurological Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, CB 8057, Saint Louis, USA

c Department of Cell Biology and Physiology, 660 S. Euclid Avenue, CB 8228, Washington University in Saint Louis, Saint Louis, USA

Abstract

SCK nanoparticles having differing core thermal characteristics were designed and evaluated as thermoresponsive drug delivery systems of doxorubicin for the killing of cancerous cells.

Graphical abstract: SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles

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Article information

https://doi.org/10.1039/B805428B
Submitted
01 Apr 2008
Accepted
02 May 2008
First published
10 Jun 2008
Chem. Commun., 2008, 3579-3581
Article type
Communication
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SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles

A. M. Nyström, Z. Xu, J. Xu, S. Taylor, T. Nittis, S. A. Stewart, J. Leonard and K. L. Wooley, Chem. Commun., 2008, 3579
DOI: 10.1039/B805428B

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