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Issue 30, 2008
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SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles

Andreas M. Nyström,a  Zhiqiang Xu,b  Jinqi Xu,a  Sara Taylor,b  Thalia Nittis,c  Sheila A. Stewart,c  Jeffrey Leonardb  and  Karen L. Wooley*a 
Author affiliations

* Corresponding authors

a Center for Materials Innovation, Department of Chemistry and Department of Radiology, Washington University in Saint Louis, Saint Louis, USA
E-mail: klwooley@artsci.wustl.edu
Fax: +1 314 935-9844
Tel: +1 314 935-7136

b Department of Neurological Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, CB 8057, Saint Louis, USA

c Department of Cell Biology and Physiology, 660 S. Euclid Avenue, CB 8228, Washington University in Saint Louis, Saint Louis, USA

Abstract

SCK nanoparticles having differing core thermal characteristics were designed and evaluated as thermoresponsive drug delivery systems of doxorubicin for the killing of cancerous cells.

Graphical abstract: SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles

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Publication details

The article was received on 01 Apr 2008, accepted on 02 May 2008 and first published on 10 Jun 2008


Article type: Communication
DOI: 10.1039/B805428B
Citation: Chem. Commun., 2008,0, 3579-3581

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    SCKs as nanoparticle carriers of doxorubicin: investigation of core composition on the loading, release and cytotoxicity profiles

    A. M. Nyström, Z. Xu, J. Xu, S. Taylor, T. Nittis, S. A. Stewart, J. Leonard and K. L. Wooley, Chem. Commun., 2008, 0, 3579
    DOI: 10.1039/B805428B

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