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Issue 22, 2008
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Catalytic enantioselective Reformatsky reaction with ketones

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Abstract

Chiral tertiary alcohols were obtained with good yields and enantioselectivities via a catalytic Reformatsky reaction with ketones, including the challenging diaryl ketones, using chiral BINOL derivatives.

Graphical abstract: Catalytic enantioselective Reformatsky reaction with ketones

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Supplementary files

Article information


Submitted
31 Jan 2008
Accepted
07 Mar 2008
First published
01 Apr 2008

Chem. Commun., 2008, 2571-2573
Article type
Communication

Catalytic enantioselective Reformatsky reaction with ketones

M. Á. Fernández-Ibáñez, B. Maciá, A. J. Minnaard and B. L. Feringa, Chem. Commun., 2008, 2571
DOI: 10.1039/B801749B

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