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Issue 10, 2008
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Formal total synthesis of triptolide

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Abstract

A new approach to the medicinally-important natural product triptolide is significantly shorter than previous syntheses, highly convergent and avoids the use of protecting groups; key features include two Diels–Alder reactions and a new deoxygenative aromatisation process.

Graphical abstract: Formal total synthesis of triptolide

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Publication details

The article was received on 04 Dec 2007, accepted on 09 Jan 2008 and first published on 30 Jan 2008


Article type: Communication
DOI: 10.1039/B718754H
Citation: Chem. Commun., 2008,0, 1226-1228

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    Formal total synthesis of triptolide

    N. A. Miller, A. C. Willis and M. S. Sherburn, Chem. Commun., 2008, 0, 1226
    DOI: 10.1039/B718754H

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