Issue 45, 2008
From the journal:

Chemical Communications

Cell adhesive hydrogels synthesised by copolymerisation of arg-protected Gly-Arg-Gly-Asp-Ser methacrylate monomers and enzymatic deprotection†

Lynne Perlin,ab   Sheila MacNeil*b  and  Stephen Rimmer*a  

* Corresponding authors

a Dept. of Chemistry, Univ. of Sheffield, Sheffield, South Yorkshire, UK
E-mail: s.rimmer@sheffield.ac.uk

b Dept. of Engineering Materials, The Kroto Research Institute, Univ. of Sheffield, Sheffield, South Yorkshire, UK
E-mail: s.macneil@sheffield.ac.uk

Abstract

This work reports the synthesis of protected Gly-Arg-Gly-Asp-Ser functionalised hydrogels, which are deprotected (and activated for cell adhesion) by reaction with glutathione-S-transferase.

Graphical abstract: Cell adhesive hydrogels synthesised by copolymerisation of arg-protected Gly-Arg-Gly-Asp-Ser methacrylate monomers and enzymatic deprotection

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Article information

DOI
https://doi.org/10.1039/B813392A
Article type
Communication
Submitted
01 Aug 2008
Accepted
08 Sep 2008
First published
09 Oct 2008

Chem. Commun., 2008, 5951-5953

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Cell adhesive hydrogels synthesised by copolymerisation of arg-protected Gly-Arg-Gly-Asp-Ser methacrylate monomers and enzymatic deprotection

L. Perlin, S. MacNeil and S. Rimmer, Chem. Commun., 2008, 5951 DOI: 10.1039/B813392A

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