Bis(benzimidazole)pyridine derivative as a new class of G-quadruplex inducing and stabilizing ligand

Guorui Li; Jing Huang; Ming Zhang; Yangyang Zhou; Dan Zhang; Zhiguo Wu; Shaoru Wang; Xiaocheng Weng; Xiang Zhou; Guangfu Yang

doi:10.1039/B807916A

Bis(benzimidazole)pyridine derivative as a new class of G-quadruplex inducing and stabilizing ligand†

Guorui Li,‡^a Jing Huang,‡^a Ming Zhang,^a Yangyang Zhou,^a Dan Zhang,^a Zhiguo Wu,^a Shaoru Wang,^a Xiaocheng Weng,^a Xiang Zhou*^ab and Guangfu Yang^b

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^a College of Chemistry and Molecular Sciences, Minist Educ, Key Lab Biomed, State Key Laboratory of Virology Wuhan University, Hubei, Wuhan, P. R. China
E-mail: xzhou@whu.edu.cn
Fax: 86-27-87336380
Tel: 86-27-61056559

^b Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan, P. R. China
E-mail: gfyang@mail.ccnu.edu.cn
Fax: 86-27-67867141
Tel: 86-27-67867706

Abstract

Two new bis(benzimidazole)aryl derivatives have been prepared and one of them has been shown to induce and stabilize formation of a G-quadruplex.

Chemical Communications

Bis(benzimidazole)pyridine derivative as a new class of G-quadruplex inducing and stabilizing ligand†

Abstract

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Bis(benzimidazole)pyridine derivative as a new class of G-quadruplex inducing and stabilizing ligand

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