Issue 31, 2008
From the journal:

Chemical Communications

Target-selective degradation of proteins by porphyrins upon visible photo-irradiation†

Shuho Tanimoto,a   Shuichi Matsumuraa  and  Kazunobu Toshima*a  

* Corresponding authors

a Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan
E-mail: toshima@applc.keio.ac.jp
Fax: +81-45-566-1576
Tel: +81-45-566-1576

Abstract

A porphyrin derivative effectively and selectively degraded the target transcription factor, human estrogen receptor-α (hER-α), upon visible light irradiation, in the absence of additives and under neutral conditions.

Graphical abstract: Target-selective degradation of proteins by porphyrins upon visible photo-irradiation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B806961A
Article type
Communication
Submitted
24 Apr 2008
Accepted
27 May 2008
First published
11 Jun 2008

Chem. Commun., 2008, 3678-3680

Permissions

Request permissions

Target-selective degradation of proteins by porphyrins upon visible photo-irradiation

S. Tanimoto, S. Matsumura and K. Toshima, Chem. Commun., 2008, 3678 DOI: 10.1039/B806961A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements