Issue 6, 2008
From the journal:

Chemical Communications

Chimeric (α-amino acid + nucleoside-β-amino acid)n peptide oligomers show sequence specific DNA/RNA recognition†

Khirud Gogoi*a  and  Vaijayanti A. Kumar*a  

* Corresponding authors

a Division of Organic Chemistry, National Chemical Laboratory, Pune, India
E-mail: k.gogoi@ncl.res.in, va.kumar@ncl.res.in
Fax: +91-20-25902624
Tel: +91-20-25902340

Abstract

An α/β-peptide backbone oligonucleotide comprising natural α-amino acids alternating with a β-amino acid component derived from thymidine sequence specifically recognizes and binds to deoxy- and ribo-oligoadenylates in triplex mode.

Graphical abstract: Chimeric (α-amino acid + nucleoside-β-amino acid)n peptide oligomers show sequence specific DNA/RNA recognition

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Article information

DOI
https://doi.org/10.1039/B716835G
Article type
Communication
Submitted
31 Oct 2007
Accepted
27 Nov 2007
First published
12 Dec 2007

Chem. Commun., 2008, 706-708

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Chimeric (α-amino acid + nucleoside-β-amino acid)n peptide oligomers show sequence specific DNA/RNA recognition

K. Gogoi and V. A. Kumar, Chem. Commun., 2008, 706 DOI: 10.1039/B716835G

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