Issue 1, 2008
From the journal:

Chemical Communications

Application of furyl-stabilized sulfur ylides to a concise synthesis of 8a-epi-swainsonine†

Jie Bia  and  Varinder K. Aggarwal*a  

* Corresponding authors

a Cantock's Close, School of Chemistry, University of Bristol, UK
E-mail: V.Aggarwal@Bristol.ac.uk
Fax: +44 117 929 8611
Tel: +44 117 954 6315

Abstract

The total synthesis of 8a-epi-swainsonine has been achieved in 20% overall yield from R-glyceraldehyde dimethylacetonide 3 through epoxidation with the achiral furyl-substituted sulfonium ylide 2d as one of the key steps.

Graphical abstract: Application of furyl-stabilized sulfur ylides to a concise synthesis of 8a-epi-swainsonine

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Article information

DOI
https://doi.org/10.1039/B713447A
Article type
Communication
Submitted
03 Sep 2007
Accepted
08 Oct 2007
First published
17 Oct 2007

Chem. Commun., 2008, 120-122

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Application of furyl-stabilized sulfur ylides to a concise synthesis of 8a-epi-swainsonine

J. Bi and V. K. Aggarwal, Chem. Commun., 2008, 120 DOI: 10.1039/B713447A

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