Fast capillary electrophoresis coupled with time-of-flight mass spectrometry under separation conditions of high electrical field strengths

Abstract

An experimental approach is presented that enables very fast capillary electrophoretic separations in conjunction with time-of-flight mass spectrometry. Field strengths exceeding 1 kV cm⁻¹ have been applied for separations of model analytes resulting in migration times on the timescale of seconds.