Transport of chloride and carboxyfluorescein through phospholipid vesicle membranes by heptapeptide amphiphiles
Abstract
Seven synthetic anion transporters (SAT) of the general form R2N-COCH2OCH2CO-(Gly)3-Pro-(Gly)3-OR′ were prepared. Three pairs of compounds each contained twin n-hexyl, n-decyl, and n-octadecyl (R) groups at the N-terminus and one contained twin n-tetradecyl groups. Three of the compounds were C-terminated by