Issue 10, 2007

Synthesis and studies of catechol-containing mycobactin S and T analogs

Abstract

The syntheses of catechol-containing mycobactin S and T analogs are described. These analogs incorporate a catechol-glycine moiety in place of the phenol-oxazoline of the naturally occurring mycobactins S and T. Studies indicated that the new siderophore analogs bind iron, and promote the growth of a number of microbes, especially strains of mycobacteria, as expected.

Graphical abstract: Synthesis and studies of catechol-containing mycobactin S and T analogs

Article information

Article type
Paper
Submitted
01 Mar 2007
Accepted
29 Mar 2007
First published
19 Apr 2007

Org. Biomol. Chem., 2007,5, 1621-1628

Synthesis and studies of catechol-containing mycobactin S and T analogs

A. J. Walz, U. Möllmann and M. J. Miller, Org. Biomol. Chem., 2007, 5, 1621 DOI: 10.1039/B703116E

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