Storable, powdered chiral zirconium complex for asymmetric aldol and hetero Diels–Alder reactions

Abstract

A storable, powdered chiral zirconium catalyst for asymmetric aldol and hetero Diels–Alder reactions has been developed. The catalyst has the same activity as that prepared in situ even after being stored for 3 months. Moreover, this chiral Zr catalyst worked efficiently not only for asymmetric aldol reactions but also for asymmetric hetero Diels–Alder reactions affording the corresponding addition products with high enantioselectivities.