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Issue 3, 2007
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Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+)

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Abstract

A chemo-enzymatic synthesis of novel caged NAADP+ without the formation of multiple cage compounds has been achieved. The biological activity of the caged NAADP+ was demonstrated by its fast uncaging in intact sea-urchin eggs.

Graphical abstract: Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+)

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Publication details

The article was received on 28 Nov 2006, accepted on 28 Nov 2006 and first published on 11 Dec 2006


Article type: Communication
DOI: 10.1039/B617344F
Citation: Org. Biomol. Chem., 2007,5, 441-443

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    Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+)

    R. Parkesh, S. R. Vasudevan, A. Berry, A. Galione, J. Dowden and G. C. Churchill, Org. Biomol. Chem., 2007, 5, 441
    DOI: 10.1039/B617344F

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