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Issue 2, 2007
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DNA and RNA induced enantioselectivity in chemical synthesis

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Abstract

One of the hallmarks of DNA and RNA structures is their elegant chirality. Using these chiral structures to induce enantioselectivity in chemical synthesis is as enticing as it is challenging. In recent years, three general approaches have been developed to achieve this, including chirality transfer by nucleotide templated synthesis, enantioselective catalysis by RNA/DNAzymes and DNA-based asymmetric catalysis. In this article the concepts behind these strategies as well as the important achievements in this field will be discussed.

Graphical abstract: DNA and RNA induced enantioselectivity in chemical synthesis

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Article information


Submitted
05 Oct 2006
Accepted
10 Nov 2006
First published
05 Dec 2006

Mol. BioSyst., 2007,3, 126-135
Article type
Review Article

DNA and RNA induced enantioselectivity in chemical synthesis

G. Roelfes, Mol. BioSyst., 2007, 3, 126
DOI: 10.1039/B614527B

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