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Issue 38, 2007
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Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

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Abstract

A hydrophobic photodynamic therapy drug, hypocrellin B (HB), was accumulated in water-solubilized natural polyelectrolyte microcapsules. The HB can be effectively encapsulated, delivered and subsequently taken up by cancer cells. These intracellular HB-loaded microcapsules show biocompatibility under darkness and high cytotoxicity after irradiation which provides the possibility of controlled delivery and release of drugs.

Graphical abstract: Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

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Publication details

The article was received on 05 Jun 2007, accepted on 10 Jul 2007 and first published on 27 Jul 2007


Article type: Paper
DOI: 10.1039/B708477C
Citation: J. Mater. Chem., 2007,17, 4018-4021

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    Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

    K. Wang, Q. He, X. Yan, Y. Cui, W. Qi, L. Duan and J. Li, J. Mater. Chem., 2007, 17, 4018
    DOI: 10.1039/B708477C

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