Issue 38, 2007
From the journal:

Journal of Materials Chemistry

Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells†

Kewei Wang,a   Qiang He,ab   Xuehai Yan,a   Yue Cui,a   Wei Qi,a   Li Duana  and  Junbai Li*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences (BNLMS), International Joint Lab, CAS Key Lab of Colloid and Interface Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China
E-mail: jbli@iccas.ac.cn
Fax: +86 10 82612629
Tel: +86 10 82614087

b Max Planck Institute of Colloids and Interfaces, Golm/Potsdam, Germany

Abstract

A hydrophobic photodynamic therapy drug, hypocrellin B (HB), was accumulated in water-solubilized natural polyelectrolyte microcapsules. The HB can be effectively encapsulated, delivered and subsequently taken up by cancer cells. These intracellular HB-loaded microcapsules show biocompatibility under darkness and high cytotoxicity after irradiation which provides the possibility of controlled delivery and release of drugs.

Graphical abstract: Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B708477C
Article type
Paper
Submitted
05 Jun 2007
Accepted
10 Jul 2007
First published
27 Jul 2007

J. Mater. Chem., 2007,17, 4018-4021

Permissions

Request permissions

Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells

K. Wang, Q. He, X. Yan, Y. Cui, W. Qi, L. Duan and J. Li, J. Mater. Chem., 2007, 17, 4018 DOI: 10.1039/B708477C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements