Jump to main content
Jump to site search

Issue 11, 2007
Previous Article Next Article

Identification of selenohomolanthionine in selenium-enriched Japanese pungent radish

Author affiliations

Abstract

Sulfur (S) and selenium (Se) are same-group elements that share, in part, a common metabolic pathway. Because a radish variant having pungent flavor (Raphanus sativus L. cv. ‘Yukibijin’) has a unique S metabolic pathway, we expected that it would also produce unique Se compounds through that metabolic pathway. Se metabolites in the radish were assigned by speciation techniques, i.e., HPLC-inductively coupled plasma mass spectrometry (ICP-MS) and HPLC-electrospray ionization tandem mass spectrometry (ESI-MS-MS). 68.5% of total Se in the selenized Japanese pungent radish was water-extractable, and the water extract contained selenate (around 45% of total Se), Se-methylselenocysteine (around 11%), an unknown Se compound tentatively named KD-1 (around 5%), and others (around 1.2%). KD-1 was assigned by ESI-MS-MS as 4,4′-selenobis[2-aminobutanoic acid] or Se-(3-amino-3-carboxypropyl)-homocysteine, commonly known as selenohomolanthionine (SeHLan). This Se compound was first identified in nature. The metabolic pathway of SeHLan was suggested to involve the phosphorylation of homoserine to produce O-phosphohomoserine, and the subsequent reaction of O-phosphohomoserine with selenohomocysteine (SeHCys).

Graphical abstract: Identification of selenohomolanthionine in selenium-enriched Japanese pungent radish

Back to tab navigation

Publication details

The article was received on 15 May 2007, accepted on 11 Jul 2007 and first published on 01 Aug 2007


Article type: Paper
DOI: 10.1039/B707348H
J. Anal. At. Spectrom., 2007,22, 1390-1396

  •   Request permissions

    Identification of selenohomolanthionine in selenium-enriched Japanese pungent radish

    Y. Ogra, T. Kitaguchi, K. Ishiwata, N. Suzuki, Y. Iwashita and K. T. Suzuki, J. Anal. At. Spectrom., 2007, 22, 1390
    DOI: 10.1039/B707348H

Search articles by author

Spotlight

Advertisements