Issue 12, 2007
From the journal:

Green Chemistry

Mannich type reactions of chlorophosphites, phosphoramides and aldehydes (ketones) under solvent-free and catalyst-free conditions—synthesis of N-phosphoramino α-aminophosphonates†

Jianfeng Zhang,a   Zhanwei Cui,a   Fei Wang,a   Yadan Wang,a   Zhiwei Miao*a  and  Ruyu Chen*a  

* Corresponding authors

a State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, China
E-mail: miaozhiwei@nankai.edu.cn
Fax: +86 22 2350 3627
Tel: +86 22 2350 8857

Abstract

A convenient and rapid method was developed for the synthesis of various N-phosphoramino α-aminoalkylphosphonates through Mannich type reactions under catalyst- and solvent-free conditions with excellent yields.

Graphical abstract: Mannich type reactions of chlorophosphites, phosphoramides and aldehydes (ketones) under solvent-free and catalyst-free conditions—synthesis of N-phosphoramino α-aminophosphonates

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Article information

DOI
https://doi.org/10.1039/B710008F
Article type
Paper
Submitted
02 Jul 2007
Accepted
26 Sep 2007
First published
11 Oct 2007

Green Chem., 2007,9, 1341-1345

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Mannich type reactions of chlorophosphites, phosphoramides and aldehydes (ketones) under solvent-free and catalyst-free conditions—synthesis of N-phosphoramino α-aminophosphonates

J. Zhang, Z. Cui, F. Wang, Y. Wang, Z. Miao and R. Chen, Green Chem., 2007, 9, 1341 DOI: 10.1039/B710008F

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