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Issue 43, 2007
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Identification of protease substrates by combinatorial profiling on TentaGel beads

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Abstract

Reacting a 65 536 member combinatorial library of octapeptides on TentaGel beads with various proteases followed by selective staining of the free amino termini at the reacted bead surface and sequence determination by amino acid analysis allowed the rapid identification of protease substrates.

Graphical abstract: Identification of protease substrates by combinatorial profiling on TentaGel beads

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Supplementary files

Article information


Submitted
05 Sep 2007
Accepted
05 Oct 2007
First published
11 Oct 2007

Chem. Commun., 2007, 4453-4455
Article type
Communication

Identification of protease substrates by combinatorial profiling on TentaGel beads

J. Kofoed and J. Reymond, Chem. Commun., 2007, 4453
DOI: 10.1039/B713595E

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