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Issue 30, 2007
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A trisulfide-linked glycoprotein

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Abstract

The first member of a novel class of chemoselective reagents, glycosyl methanedithiosulfonates, has been synthesized, identified and employed in the first examples of chemical, site-selective construction of a trisulfide-modified protein with complete conversion.

Graphical abstract: A trisulfide-linked glycoprotein

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Submitted
03 May 2007
Accepted
11 Jun 2007
First published
04 Jul 2007

Chem. Commun., 2007, 3145-3147
Article type
Communication

A trisulfide-linked glycoprotein

G. J. L. Bernardes, J. P. Marston, A. S. Batsanov, J. A. K. Howard and B. G. Davis, Chem. Commun., 2007, 3145
DOI: 10.1039/B706682A

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