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Issue 14, 2007
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Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

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Abstract

2-(4-Methoxybenzyloxy)-4-methylquinoline reacts with methyl triflate in the presence of alcohols to generate a neutral organic salt that transfers the para-methoxybenzyl (PMB) protecting group onto alcohols in high yield and under mild conditions.

Graphical abstract: Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

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Publication details

The article was received on 08 Dec 2006, accepted on 13 Feb 2007 and first published on 26 Feb 2007


Article type: Communication
DOI: 10.1039/B617926F
Citation: Chem. Commun., 2007,0, 1436-1437
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    Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

    E. O. Nwoye and G. B. Dudley, Chem. Commun., 2007, 0, 1436
    DOI: 10.1039/B617926F

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