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Issue 24, 2007
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Organocatalytic enantioselective aza-Michael reaction of nitrogen heterocycles and α,β-unsaturated aldehydes

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Abstract

The asymmetric organocatalytic aza-Michael reaction of several nitrogen heterocycles and α,β-unsaturated aldehydes has been studied in detail; under the optimised conditions, the conjugate addition products have been obtained in high to excellent enantioselectivities.

Graphical abstract: Organocatalytic enantioselective aza-Michael reaction of nitrogen heterocycles and α,β-unsaturated aldehydes

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Publication details

The article was received on 18 Jan 2007, accepted on 28 Feb 2007 and first published on 19 Mar 2007


Article type: Communication
DOI: 10.1039/B700831G
Citation: Chem. Commun., 2007,0, 2509-2511

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    Organocatalytic enantioselective aza-Michael reaction of nitrogen heterocycles and α,β-unsaturated aldehydes

    U. Uria, J. L. Vicario, D. Badía and L. Carrillo, Chem. Commun., 2007, 0, 2509
    DOI: 10.1039/B700831G

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