Issue 23, 2007

Supramolecular synthon polymorphism in 2 : 1 co-crystal of 4-hydroxybenzoic acid and 2,3,5,6-tetramethylpyrazine

Abstract

Co-crystals of 4-hydroxybenzoic acid and 2,3,5,6-tetramethylpyrazine (2 : 1) exhibit the first supramolecular synthon polymorphism in a co-crystal; metastable anti-hierarchic polymorph I converts to stable hierarchic form II.

Graphical abstract: Supramolecular synthon polymorphism in 2 : 1 co-crystal of 4-hydroxybenzoic acid and 2,3,5,6-tetramethylpyrazine

Supplementary files

Article information

Article type
Communication
Submitted
04 Jan 2007
Accepted
14 Feb 2007
First published
09 Mar 2007

Chem. Commun., 2007, 2375-2377

Supramolecular synthon polymorphism in 2 : 1 co-crystal of 4-hydroxybenzoic acid and 2,3,5,6-tetramethylpyrazine

B. R. Sreekanth, P. Vishweshwar and K. Vyas, Chem. Commun., 2007, 2375 DOI: 10.1039/B700082K

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