Issue 14, 2007
From the journal:

Chemical Communications

Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

Ernest O. Nwoyea  and  Gregory B. Dudley*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL, USA
E-mail: gdudley@chem.fsu.edu
Fax: 850-644-8281
Tel: 850-644-2333

Abstract

2-(4-Methoxybenzyloxy)-4-methylquinoline reacts with methyl triflate in the presence of alcohols to generate a neutral organic salt that transfers the para-methoxybenzyl (PMB) protecting group onto alcohols in high yield and under mild conditions.

Graphical abstract: Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

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Article information

DOI
https://doi.org/10.1039/B617926F
Article type
Communication
Submitted
08 Dec 2006
Accepted
13 Feb 2007
First published
26 Feb 2007

Chem. Commun., 2007, 1436-1437

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Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

E. O. Nwoye and G. B. Dudley, Chem. Commun., 2007, 1436 DOI: 10.1039/B617926F

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