Issue 13, 2007
From the journal:

Chemical Communications

Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials†

Randy Mellaerts,a   Caroline A. Aerts,a   Jan Van Humbeeck,b   Patrick Augustijns,c   Guy Van den Mooterc  and  Johan A. Martens*a  

* Corresponding authors

a Centre for Surface Chemistry and Catalysis, Kasteelpark Arenberg 23, Catholic University of Leuven, Heverlee, Belgium
E-mail: johan.martens@biw.kuleuven.be
Fax: +32 16 321998
Tel: +32 16 321637

b Department of Metallurgy and Materials Engineering, Kasteelpark Arenberg 44, Catholic University of Leuven, Heverlee, Belgium

c Laboratory for Pharmacotechnology and Biopharmacy, O&N2, Herestraat 49-box 921, Catholic University of Leuven, Leuven, Belgium

Abstract

This in vitro study reports on the enhanced release of the hydrophobic drug itraconazole from the ordered mesoporous SBA-15 silica material and on the existence of a critical mesopore diameter for enhancing release.

Graphical abstract: Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials

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Article information

DOI
https://doi.org/10.1039/B616746B
Article type
Communication
Submitted
16 Nov 2006
Accepted
10 Jan 2007
First published
29 Jan 2007

Chem. Commun., 2007, 1375-1377

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Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials

R. Mellaerts, C. A. Aerts, J. V. Humbeeck, P. Augustijns, G. V. den Mooter and J. A. Martens, Chem. Commun., 2007, 1375 DOI: 10.1039/B616746B

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