Issue 4, 2007

Tri- and hexavalent mannoside clusters as potential inhibitors of type 1 fimbriated bacteria using pentaerythritol and triazole linkages

Abstract

Several oligomannoside clusters having a hundred-fold increase in affinities toward E. coli were synthesized by Cu(I)-catalyzed [1,3]-dipolar cycloadditions using pentaerythritol scaffolds bearing either alkyne or azide functionalities.

Graphical abstract: Tri- and hexavalent mannoside clusters as potential inhibitors of type 1 fimbriated bacteria using pentaerythritol and triazole linkages

Article information

Article type
Communication
Submitted
30 Aug 2006
Accepted
31 Oct 2006
First published
23 Nov 2006

Chem. Commun., 2007, 380-382

Tri- and hexavalent mannoside clusters as potential inhibitors of type 1 fimbriated bacteria using pentaerythritol and triazole linkages

M. Touaibia, T. C. Shiao, A. Papadopoulos, J. Vaucher, Q. Wang, K. Benhamioud and R. Roy, Chem. Commun., 2007, 380 DOI: 10.1039/B612471B

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