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Issue 12, 2006
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Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs

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Abstract

A linear type of several low molecular weight CXCR4 antagonists were developed based on T140 analogs, which were previously found to be strong CXCR4 antagonists that block X4-HIV-1 entry and have inhibitory activities against cancer metastasis/progression and rheumatoid arthritis.

Graphical abstract: Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs

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Publication details

The article was received on 14 Mar 2006, accepted on 24 Apr 2006 and first published on 12 May 2006


Article type: Communication
DOI: 10.1039/B603818B
Citation: Org. Biomol. Chem., 2006,4, 2354-2357

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    Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs

    H. Tamamura, H. Tsutsumi, H. Masuno, S. Mizokami, K. Hiramatsu, Z. Wang, J. O. Trent, H. Nakashima, N. Yamamoto, S. C. Peiper and N. Fujii, Org. Biomol. Chem., 2006, 4, 2354
    DOI: 10.1039/B603818B

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