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Issue 5, 2006
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Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

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Abstract

Phosphoramidites are effective chiral ligands in the rhodium catalyzed addition of arylboronic acids to aldehydes providing up to 75% enantioselectivity and up to 96% isolated yield.

Graphical abstract: Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

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Article information


Submitted
03 Jan 2006
Accepted
21 Jan 2006
First published
31 Jan 2006

Org. Biomol. Chem., 2006,4, 773-775
Article type
Communication

Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

R. B. C. Jagt, P. Y. Toullec, J. G. de Vries, B. L. Feringa and A. J. Minnaard, Org. Biomol. Chem., 2006, 4, 773
DOI: 10.1039/B518311A

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