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Issue 5, 2006
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Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

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Abstract

Phosphoramidites are effective chiral ligands in the rhodium catalyzed addition of arylboronic acids to aldehydes providing up to 75% enantioselectivity and up to 96% isolated yield.

Graphical abstract: Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

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Publication details

The article was received on 03 Jan 2006, accepted on 21 Jan 2006 and first published on 31 Jan 2006


Article type: Communication
DOI: 10.1039/B518311A
Citation: Org. Biomol. Chem., 2006,4, 773-775

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    Rhodium/phosphoramidite-catalyzed asymmetric arylation of aldehydes with arylboronic acids

    R. B. C. Jagt, P. Y. Toullec, J. G. de Vries, B. L. Feringa and A. J. Minnaard, Org. Biomol. Chem., 2006, 4, 773
    DOI: 10.1039/B518311A

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