Issue 21, 2006
From the journal:

Organic & Biomolecular Chemistry

Synthesis of the penta-oxazole core of telomestatin in a convergent approach to poly-oxazolemacrocycles

Charles M. Marson*a  and  Mona Saadia  

* Corresponding authors

a Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London, UK
E-mail: c.m.marson@ucl.ac.uk
Fax: +44 (0)207 679 7463
Tel: +44 (0)207 679 4712

Abstract

A protocol for the construction of poly-oxazoles with consecutive 2,4′-linkages is described, and has afforded an efficient route to a penta-oxazole which demarcates a route to telomestatin and related macrocyclic poly-oxazole systems.

Graphical abstract: Synthesis of the penta-oxazole core of telomestatin in a convergent approach to poly-oxazole macrocycles

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Article information

DOI
https://doi.org/10.1039/B613791C
Article type
Communication
Submitted
21 Sep 2006
Accepted
21 Sep 2006
First published
02 Oct 2006

Org. Biomol. Chem., 2006,4, 3892-3893

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Synthesis of the penta-oxazole core of telomestatin in a convergent approach to poly-oxazole macrocycles

C. M. Marson and M. Saadi, Org. Biomol. Chem., 2006, 4, 3892 DOI: 10.1039/B613791C

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