Issue 23, 2006
From the journal:

Organic & Biomolecular Chemistry

A novel approach to functionalised pyridazinone arrays†

Matthew D. Helm,a   Andrew Plantb  and  Joseph P. A. Harrity*a  

* Corresponding authors

a Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, UK
E-mail: j.harrity@sheffield.ac.uk
Fax: +44 (0114) 222 9346
Tel: +44 (0114) 222 9496

b Research Chemistry, Syngenta, Jealott's Hill International Research Centre, Bracknell, Berkshire, UK

Abstract

A series of 3,6-dichloro-1H-pyridazin-4-ones have been prepared via the cycloaddition of 3,6-dichlorotetrazine with alkynylboronates, and their employment as useful synthetic intermediates was highlighted through a selection of highly regioselective C–O, C–S and C–C bond forming reactions.

Graphical abstract: A novel approach to functionalised pyridazinone arrays

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Article information

DOI
https://doi.org/10.1039/B613223E
Article type
Communication
Submitted
12 Sep 2006
Accepted
17 Oct 2006
First published
26 Oct 2006

Org. Biomol. Chem., 2006,4, 4278-4280

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A novel approach to functionalised pyridazinone arrays

M. D. Helm, A. Plant and J. P. A. Harrity, Org. Biomol. Chem., 2006, 4, 4278 DOI: 10.1039/B613223E

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