Issue 15, 2006
From the journal:

Organic & Biomolecular Chemistry

Efficient conversion of nitronate into nitrile oxide using cyanuric chloride. One-pot synthesis of bicyclic isoxazolines and isoxazoles from nitroalkenes†

Shijay Gao,a   Zhijay Tu,a   Chun-Wei Kuo,a   Ju-Tsung Liu,a   Cheng-Ming Chua  and  Ching-Fa Yao*a  

* Corresponding authors

a Department of Chemistry, National Taiwan Normal University 88, Sec. 4, Tingchow Road, Taipei, Taiwan, ROC
E-mail: cheyaocf@scc.ntnu.edu.tw
Fax: +886 2 29309092

Abstract

Bicyclic isoxazolines and isoxazoles are obtained in good yields by proceeding through a convenient one-pot, two-step procedure utilizing 2,4,6-trichloro-1,3,5-triazine (TCT) as a dehydrating agent.

Graphical abstract: Efficient conversion of nitronate into nitrile oxide using cyanuric chloride. One-pot synthesis of bicyclic isoxazolines and isoxazoles from nitroalkenes

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Article information

DOI
https://doi.org/10.1039/B606717D
Article type
Paper
Submitted
12 May 2006
Accepted
05 Jun 2006
First published
28 Jun 2006

Org. Biomol. Chem., 2006,4, 2851-2857

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Efficient conversion of nitronate into nitrile oxide using cyanuric chloride. One-pot synthesis of bicyclic isoxazolines and isoxazoles from nitroalkenes

S. Gao, Z. Tu, C. Kuo, J. Liu, C. Chu and C. Yao, Org. Biomol. Chem., 2006, 4, 2851 DOI: 10.1039/B606717D

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