Issue 5, 2006
From the journal:

Organic & Biomolecular Chemistry

Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers†

Marine Guillot,a   Sara Eisler,a   Kathrin Weller,b   Hans P. Merkle,b   Jean-Louis Gallanic  and  François Diederich*a  

* Corresponding authors

a Laboratorium für Organische Chemie, ETH-Zürich, Zürich, Switzerland
E-mail: diederich@org.chem.ethz.ch
Fax: +41 44 63 21109
Tel: +41 44 63 22992

b Institut für Pharmazeutische Wissenschaften, ETH-Zürich, Zürich, Switzerland
E-mail: hmerkle@pharma.ethz.ch
Fax: +41 44 63 31314
Tel: +41 44 63 37310

c Institut de Physique et Chimie des Matériaux de Strasbourg, Strasbourg Cedex, France
E-mail: gallani@ipcms.u-strasbg.fr
Fax: +33 388 107246
Tel: +33 388 107164

Abstract

A library of novel amphiphilic, self-assembling dendrimers was designed and synthesised to evaluate the effects of structural changes on transfection efficiency.

Graphical abstract: Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers

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Article information

DOI
https://doi.org/10.1039/B518174G
Article type
Communication
Submitted
21 Dec 2005
Accepted
13 Jan 2006
First published
26 Jan 2006

Org. Biomol. Chem., 2006,4, 766-769

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Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers

M. Guillot, S. Eisler, K. Weller, H. P. Merkle, J. Gallani and F. Diederich, Org. Biomol. Chem., 2006, 4, 766 DOI: 10.1039/B518174G

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