Nucleophilic opening of epoxyazepanes: expanding the family of polyhydroxyazepane-based glycosidase inhibitors†
Abstract
A range of new tetra- and pentahydroxylated seven-membered iminoalditols has been efficiently synthesized from
* Corresponding authors
a
Ecole Normale Supérieure, Département de Chimie, UMR 8642 associée au CNRS, 24 rue Lhomond, Paris Cedex 05, France
E-mail:
yves.bleriot@ens.fr
Fax: +33 1 44 32 33 97
Tel: +33 1 44 32 33 35
b Laboratoire de glycochimie et de synthèse asymétrique, Swiss Federal Institute of Technology (EPFL) BCH, Lausanne-Dorigny, Switzerland
c Institut de Chimie Moléculaire (FR 2769), Université Pierre et Marie Curie-Paris 6, Paris, France
A range of new tetra- and pentahydroxylated seven-membered iminoalditols has been efficiently synthesized from
H. Li, C. Schütz, S. Favre, Y. Zhang, P. Vogel, P. Sinaÿ and Y. Blériot, Org. Biomol. Chem., 2006, 4, 1653 DOI: 10.1039/B518117H
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