Issue 4, 2006
From the journal:

Organic & Biomolecular Chemistry

PegPhos: a monodentate phosphoramiditeligand for enantioselective rhodium-catalysed hydrogenation in water†

Rob Hoen,b   Stephane Leleu,a   Peter N. M. Botman,a   Vanessa A. M. Appelman,a   Ben L. Feringa,b   Henk Hiemstra,a   Adriaan J. Minnaard*b  and  Jan H. van Maarseveen*a  

* Corresponding authors

a Institute of Molecular Chemistry, University of Amsterdam, Nieuwe Achtergracht 129, Amsterdam, The Netherlands
E-mail: jvm@science.uva.nl

b Stratingh Institute, University of Groningen, Nijenborgh 4, Groningen, The Netherlands
E-mail: a.j.minnaard@rug.nl

Abstract

A BICOL derived monodentate phosphoramidite ligand gives ee's up to 89% in the enantioselective Rh-catalysed hydrogenation of N-acyl dehydroalanine using water as the solvent.

Graphical abstract: PegPhos: a monodentate phosphoramidite ligand for enantioselective rhodium-catalysed hydrogenation in water

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B517096F
Article type
Communication
Submitted
01 Dec 2005
Accepted
03 Jan 2006
First published
13 Jan 2006

Org. Biomol. Chem., 2006,4, 613-615

Permissions

Request permissions

PegPhos: a monodentate phosphoramidite ligand for enantioselective rhodium-catalysed hydrogenation in water

R. Hoen, S. Leleu, P. N. M. Botman, V. A. M. Appelman, B. L. Feringa, H. Hiemstra, A. J. Minnaard and J. H. van Maarseveen, Org. Biomol. Chem., 2006, 4, 613 DOI: 10.1039/B517096F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements