A direct, efficient synthesis of unsymmetrically substituted bis(arylidene)alkanones

Abstract

A direct method to unsymmetrically substituted bis(arylidene)alkanones by sequential, selective condensation reactions is reported. Analytically pure compounds were obtained in high yield using atom-economical reactions and without the need for purification of the final products. Although a two-step process could be conducted in one pot by three different methods, recrystallisation was required.