Direct synthesis of (imine)platinum(ii) complexes by iminoacylation of ketoximes with activated organonitrile ligands
Abstract
The metal-mediated iminoacylation of NOH (1a R1 = R2 = Me; 1b R1 = Me, R2 = Et; 1c R1R2 = C4H8; 1d R1R2 = C5H10) upon treatment with the platinum(II) complex trans-[PtCl2(NCCH2CO2Me)2] 2a with an organonitrile bearing an acceptor group proceeds under mild conditions in dry CH2Cl2 to give the trans-[PtCl2{NH
C(CH2CO2Me)ON
CR1R2}2] 3a–d isomers in moderate yield. The reaction of those
C(CH2Cl)ON
CR1R2}2] 3e–h and 4e–h in moderate to good yield. These reactions are greatly accelerated by microwave irradiation to give, with higher yields (ca. 75%), the same products which were characterized by