Issue 41, 2006

Stereoselective synthesis of N-alkylaziridines from N-chloroamines

Abstract

We report the first racemic and stereoselective synthesis of cis- and trans-N-alkylaziridines viaN-chloroamines; using this methodology an N-3,4,5-trimethoxybenzylaziridine was synthesised and efficiently cleaved, affording the corresponding NH aziridine in high yield.

Graphical abstract: Stereoselective synthesis of N-alkylaziridines from N-chloroamines

Supplementary files

Article information

Article type
Communication
Submitted
20 Jun 2006
Accepted
24 Jul 2006
First published
05 Sep 2006

Chem. Commun., 2006, 4338-4340

Stereoselective synthesis of N-alkylaziridines from N-chloroamines

S. P. Bew, D. L. Hughes, N. J. Palmer, V. Savic, K. M. Soapi and M. A. Wilson, Chem. Commun., 2006, 4338 DOI: 10.1039/B608504K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements