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Issue 45, 2006
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Tetramethylpyridiniumporphyrazines—a new class of G-quadruplex inducing and stabilising ligands

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Abstract

3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.

Graphical abstract: Tetramethylpyridiniumporphyrazines—a new class of G-quadruplex inducing and stabilising ligands

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Publication details

The article was received on 15 Aug 2006, accepted on 12 Sep 2006 and first published on 27 Sep 2006


Article type: Communication
DOI: 10.1039/B611731G
Citation: Chem. Commun., 2006,0, 4685-4687

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    Tetramethylpyridiniumporphyrazines—a new class of G-quadruplex inducing and stabilising ligands

    D. P. N. Gonçalves, R. Rodriguez, S. Balasubramanian and J. K. M. Sanders, Chem. Commun., 2006, 0, 4685
    DOI: 10.1039/B611731G

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