Issue 34, 2006
From the journal:

Chemical Communications

Introduction of single mutation changes arylmalonate decarboxylase to racemase†

Yosuke Terao,a   Kenji Miyamotoa  and  Hiromichi Ohta*a  

* Corresponding authors

a Department of Biosciences and Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Japan
E-mail: hohta@bio.keio.ac.jp
Fax: +81-45-566-1551
Tel: +81-45-566-1703

Abstract

The introduction of only one mutation based on the estimated reaction mechanism endowed arylmalonate decarboxylase with a racemase activity, which catalyses racemisation of α-arylpropionates.

Graphical abstract: Introduction of single mutation changes arylmalonate decarboxylase to racemase

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Article information

DOI
https://doi.org/10.1039/B607211A
Article type
Communication
Submitted
22 May 2006
Accepted
25 Jul 2006
First published
03 Aug 2006

Chem. Commun., 2006, 3600-3602

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Introduction of single mutation changes arylmalonate decarboxylase to racemase

Y. Terao, K. Miyamoto and H. Ohta, Chem. Commun., 2006, 3600 DOI: 10.1039/B607211A

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