Issue 29, 2006

Microarrays of heparinoligosaccharides obtained by nitrous acid depolymerization of isolated heparin

Abstract

Heparin oligosaccharides derived by nitrous acid depolymerization of heparin have been immobilized on amine-coated glass slides. The formation of a Schiff base creates heparin chips that are a suitable platform for the high-throughput analysis of carbohydrate–protein interactions.

Graphical abstract: Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

Supplementary files

Article information

Article type
Communication
Submitted
12 Apr 2006
Accepted
01 Jun 2006
First published
14 Jun 2006

Chem. Commun., 2006, 3116-3118

Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

J. L. de Paz, D. Spillmann and P. H. Seeberger, Chem. Commun., 2006, 3116 DOI: 10.1039/B605318A

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