Issue 26, 2006

Insertion of two pyrene moieties into oligodeoxyribonucleotides for the efficient detection of deletion polymorphisms

Abstract

For the detection of deletion polymorphisms, two pyrene moieties are tethered to an oligodeoxyribonucleotide (ODN) on both sides of the intervening base; one- and two-base deletions can be selectively detected by the strength of the excimer emission.

Graphical abstract: Insertion of two pyrene moieties into oligodeoxyribonucleotides for the efficient detection of deletion polymorphisms

Supplementary files

Article information

Article type
Communication
Submitted
03 Apr 2006
Accepted
11 May 2006
First published
06 Jun 2006

Chem. Commun., 2006, 2768-2770

Insertion of two pyrene moieties into oligodeoxyribonucleotides for the efficient detection of deletion polymorphisms

H. Kashida, H. Asanuma and M. Komiyama, Chem. Commun., 2006, 2768 DOI: 10.1039/B604776A

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