Fullerene (C60) immunoconjugates: interaction of water-soluble C60 derivatives with the murine anti-gp240 melanoma antibody

Jared M. Ashcroft; Dmitri A. Tsyboulski; Keith B. Hartman; Tatiana Y. Zakharian; John W. Marks; R. Bruce Weisman; Michael G. Rosenblum; Lon J. Wilson

doi:10.1039/B601717G

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Fullerene (C₆₀) immunoconjugates: interaction of water-soluble C₆₀ derivatives with the murine anti-gp240 melanoma antibody†

Jared M. Ashcroft,^a Dmitri A. Tsyboulski,^a Keith B. Hartman,^a Tatiana Y. Zakharian,^a John W. Marks,^b R. Bruce Weisman,^a Michael G. Rosenblum^b and Lon J. Wilson*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry, Smalley Institute for Nanoscale Science and Technology, and the Center for Biological and Environmental Nanotechnology, MS 60, Rice University, Houston, Texas 77005, USA
E-mail: durango@rice.edu
Fax: +1 713-348-5155
Tel: +1 713-348-3268

^b Immunopharmacology and Targeted Therapy Section, Department of Experimental Therapeutics, MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas 77030, USA

Abstract

The first fullerene (C₆₀) immunoconjugates have been prepared and characterized as an initial step toward the development of fullerene immunotherapy (FIT).

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Experimantal and instrumental detail PDF (2022K)

Article information

DOI: https://doi.org/10.1039/B601717G
Article type: Communication
Submitted: 07 Feb 2006
Accepted: 08 May 2006
First published: 09 Jun 2006

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Chem. Commun., 2006, 3004-3006

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Fullerene (C₆₀) immunoconjugates: interaction of water-soluble C₆₀ derivatives with the murine anti-gp240 melanoma antibody

J. M. Ashcroft, D. A. Tsyboulski, K. B. Hartman, T. Y. Zakharian, J. W. Marks, R. B. Weisman, M. G. Rosenblum and L. J. Wilson, Chem. Commun., 2006, 3004 DOI: 10.1039/B601717G

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